E-Cigs Vapes & Pod-Based Tobacco Prevention Toolkit Stanford Medicine

If passed, this ban would have averted over 650 uwell sale,000 deaths over the next 40 years, and would have led 4.5 million Americans who smoke menthol cigarettes to quit entirely. This delay means that menthol cigarettes will continue to cause suffering and kill many more people of color, LGBTQ+ individuals, and those with lower incomes who use menthol cigarettes at higher rates. But marketing and advertising campaigns by some of the biggest companies such as Juul targeted young people by offering vaping as a cool and safe activity. The result has been “an epidemic” of vaping among teens and even younger children who become addicted to nicotine, experts say. I have heard that electronic cigarettes have been banned completely from commercial airlines. Fears that e-cigarettes have made smoking seem normal again or even led to people taking up tobacco smoking are not so far being realised based on the evidence assessed by this important independent review.

A P-value  ≤0.05 was considered to represent a statistically significant difference. You can buy them from specialist vape shops, some pharmacies and other retailers, or on the internet. As with all rechargeable electrical devices, the correct charger should be used and the device should not be left charging unattended or overnight. There have been instances of e-cigarettes exploding or catching fire. EBook files are now available for a large number of reports on the NAP.edu website.

Nicotine exposure damages adolescent brain development (learning, attention, impulse control), which does not end until one’s mid-20s. It also contributes to the hardening of the arterial walls, which in turn, may lead to a cardiac event. The aerosol, or “vapor,” produced by e-cigarettes is not a harmless, flavorful water vapor.

Because the liquid solution is converted into an aerosol vapor, e-cigarette use is often referred to as “vaping,” rather than smoking. Electronic smoking devices (or ESDs), which are often called e-cigarettes, heat and vaporize a solution that typically contains nicotine. The devices are metal or plastic tubes that contain a cartridge filled with a liquid that is vaporized by a battery-powered heating element. The aerosol is inhaled by the user when they draw on the device, as they would a regular tobacco cigarette, and the user exhales the aerosol into the environment. Nicotine is a highly addictive substance found in tobacco products, including cigarettes, cigars, chewing tobacco, e-cigarettes, and pouches.

Nicotine poisoning is the result of having too much nicotine in your body. Most cases resulted from the use of nicotine as an insecticide, accidental ingestion of tobacco or ingestion of nicotine-containing plants. From October this year it will be an offence to sell e-cigarettes to anyone under the age of 18 or to buy e-cigarettes for them. The government is consulting on a comprehensive array of regulations under the European Tobacco Products Directive. Suppositories are products designed to be inserted into the rectum or vagina, where they release the drug as they dissolve.

The Department has sent a statewide health alert to health care providers and local health departments following recent reports of severe lung disease in people who have used vaping products. The cytotoxic and pro-inflammatory effects of different e-cigarette flavouring chemicals were also tested on two human monocytic cell lines—mono mac 6 (MM6) and U937 [86]. Among the flavouring chemicals tested, CAD was found to be the most toxic and O-vanillin and pentanedione also showed significant cytotoxicity; by contrast, acetoin, diacetyl, maltol, and coumarin did not show any toxicity at the concentrations assayed (10–1000 µM). Of interest, a higher toxicity was evident when combinations of different flavours or mixed equal proportions of e-liquids from 10 differently flavoured e-liquids were tested, suggesting that vaping a single flavour is less toxic than inhaling mixed flavours [86]. Also, all the tested flavours produced significant levels of ROS in a cell-free ROS production assay.

Innokin are known widely as the premier manufacturer of starter vape kits, though they also have a great deal of experience in producing sub-ohm kits, mods and tanks. In January 2023, a California judge gave preliminary approval for Juul’s $255 million offer to settle a class action involving economic loss. Members of the class claimed they would have paid less or not bought Juul’s products had the company not falsely advertised.

Because e-cigarettes contain nicotine derived from tobacco, they are now subject to government regulation as tobacco products. In December 2019, the federal government raised the legal minimum age of sale of tobacco products from 18 to 21 years, and in January 2020, the FDA issued a policy on the sale of flavored vaping cartridges. Products marketed for therapeutic purposes (for example, marketed as a product to help people quit smoking) are regulated by FDA’s Center for Drug Evaluation and Research (CDER). FDA published a rule clarifying when products made or derived from tobacco are regulated as tobacco products, drugs, and/ or devices.

This is because e-cigarettes don’t contain cancer-causing tobacco, and most of the toxic chemicals found in cigarettes are not in e-cigarettes. E-cigarettes, or electronic cigarettes, are battery-operated smoking devices. At this time, the New Jersey Department of Health is investigating multiple reports from healthcare facilities of severe lung illness in people who report vaping. Cases in New Jersey have been primarily reported among persons between the ages of 15 to 75 with no significant past medical history.

However, e-cigarettes containing 20 mg/mL of nicotine are more equivalent to normal cigarettes, based on the delivery of approximately 1 mg of nicotine every 5 min [40]. ESD aerosol is a new source of pollution and toxins being emitted into the environment. We do not know the long-term health effects of ESD use and although the industry marketing of the product implies that these products are harmless, the aerosol that ESD emit is not purely water vapor. In conclusion, we sought to replicate the potential effects of exposure of the user in an acute in vitro system using our vaping-condensate technique.

However, varenicline is already on the market in the U.S. in generic versions while cytisinicline has not yet received FDA approval and is not currently available for use by patients. To date, there is no state excise or special tax placed on e-cigarettes. These products, also known as e-cigarettes, don’t create smoke—because they don’t burn tobacco. Voopoo vape kits have an almost space-age feel due to the technological advancements their devices often herald for the entire vape industry.

The FDA has never approved an e-cigarette as a smoking cessation device. Studies into whether the devices help people quit smoking have yielded mixed results. When Juul first hit the market in 2015, its vape liquid contained much higher levels of nicotine than e-cigs that had already been on the market. Each Juul pod contains as much nicotine as 20 regular cigarettes, according to the Centers for Disease Control and Prevention.

Side effects are usually easily managed and should not stop you from vaping as a way to quit smoking. Most of the harmful chemicals in tobacco smoke, including tar and carbon monoxide, are not contained in vape aerosol. Evidence shows that vaping is substantially less harmful than smoking. Vaping exposes users to far fewer toxins and at lower levels than smoking cigarettes. You’re roughly twice as likely to quit smoking if you use a nicotine vape compared with other nicotine replacement products, like patches or gum. The routines and rituals of smoking can be hard to stop, so vaping can help you gradually let go of these while immediately reducing the health risks of smoking cigarettes.

The U.S. Preventive Services Task Force, a group of health experts that makes recommendations about preventive health care, has concluded that evidence is insufficient to recommend e-cigarettes for smoking cessation in adults, including pregnant women. Participants were first recruited in May 2021, and data analysis was conducted in December 2022. But it is not responsible for the harmful effects of smoking, and nicotine does not cause cancer. People have safely used nicotine replacement therapy (NRT) to stop smoking for many years. Nicotine replacement therapy is prescribed by doctors or is available from pharmacies. They usually contain nicotine, which is the addictive chemical in cigarettes.

Only 23 e-cigarette and vaping products have been authorized to be sold in the U.S. by the federal Food and Drug Administration. But there are thousands of products available in retail and online shops, said Charlie Giblin, a retired criminal investigator supervisor with the state Department of the Treasury, which regulates vaping and tobacco products. Electronic cigarettes (e-cigarettes) are devices made to resemble cigarettes.

All adults who smoke conventional cigarettes or other combustible (burned) tobacco products should be advised to quit smoking at the earliest opportunity, recognizing that quitting is hard and often takes repeated, dedicated efforts. Individuals can also seek cessation support by calling QUIT-NOW or ACS-2345. Middle and high school students are the largest users of these smoking replacements. Recent youth tobacco surveys found e-cigarette use had surpassed conventional cigarettes as the most commonly used tobacco product among youth. These surveys also revealed that many young people consider vaping to be safe and are not aware that e-cigarettes contain nicotine. It is easy for middle school and high school students to conceal their use of vaping devices because of their appearance as everyday objects.

But it’s undeniable that they have less conventional carcinogens compared to oral tobacco products, like chewing tobacco and whatnot. About ORCA-V1The Phase 2 ORCA-V1 trial evaluated 160 adults who used e-cigarettes on a daily basis at five clinical trial locations in the United States. ORCA-V1 participants were randomized to receive 3mg cytisinicline three times daily or placebo for 12 weeks in combination with standard cessation behavioral support. The dose and administration of cytisinicline in the ORCA-V1 study is identical to that used in the Phase 3 registrational trials for smoking cessation. ORCA-V1 was supported in part by the National Institute on Drug Abuse (NIDA) of the NIH through grant funding which was awarded in two phases totaling $2.8 million. “A proliferation of establishments selling electronic smoking devices or electronic smoking device paraphernalia, particularly when concentrated geographically, can have a negative impact on public health, safety and welfare,” the moratorium said.

Youth and young adults had more than three times the odds of using fruit-flavored e-cigarettes compared to older adults. A 2017 study by Truth Initiative found 25% of survey respondents, aged 15-24, recognized a JUUL e-cigarette device when shown a photo of the product. And among those who recognized JUUL, 25% reported that use of this product is called “JUULing,” indicating that this product is so distinctive, it’s perceived as its own category. However, it’s likely that recognition is higher now given that JUUL’s sales market share continued to rise throughout 2018 and top out at 75% among U.S. e-cigarette sales in July 2019. With Americans puffing less each year, the cigarette industry sees ESDs and other smokeless products as financial saviors.

In 2018, the rapid rise of tobacco products led the U.S. surgeon general to issue an advisory about the youth e-cigarette “epidemic.” In 2019, youth e-cigarette use increased to even higher levels. While the most recent studies show a decrease in youth use in 2020, the rate is still alarmingly high with nearly one in five high school students reporting current e-cigarette use. In May 2021, the China Health Commission (equivalent to Ministry of Health) published China’s Report on the Health Hazards of Smoking 2020,26 which concluded that EC use is unsafe.

The report also reveals a large increase in the concentration of nicotine in disposable e-cigarettes sold between 2015 and 2018. In 2015, disposable products on average contained 25 mg of nicotine per ml of e-liquid. This concentration increased nearly 60% to 39.5 mg/ml in 2018, increasing their addictiveness. Cartridge-based e-cigarettes contained even higher nicotine concentrations, with the most popular products having concentrations between 51 and 61 mg/ml, while the sale of nicotine-free cartridges was negligible. On the other hand, one potential challenge that the researchers uncovered in the results indicated that people without a cigarette smoking history – in other words, those who have only ever used e-cigarettes – might have a harder time quitting.

Nicotine poisoning in children comes mostly from eating cigarettes and consuming liquid nicotine — either from absorbing spilled nicotine through their skin or through the mucous membrane in their mouth or from swallowing liquid nicotine. Death from nicotine poisoning is not common in adults because of their larger body size. However, using more than one type of nicotine-containing product at the same time can increase your risk. With these products, it’s the liquid nicotine that can be dangerous, especially to children.

In this line, the maximum concentration tested (1000 µM) would correspond to approximately 80 to 150 ppm, which is far higher than the levels found in aerosols of some of these compounds [84]. Moreover, on a day-to-day basis, lungs of e-cigarette users are not constantly exposed to these chemicals for 24 h at these concentrations. Similar limitations were found when five of seven flavourings were found to cause cytotoxicity in human bronchial epithelial cells [87]. On March 27, 2021, Congress amended the Preventing All Cigarette Trafficking (PACT Act) to include new regulations regarding the delivery and sales of electronic nicotine delivery systems (ENDS), which include e-cigarettes, “vapes”, flavored and smokeless tobacco. Electronic cigarettes (e-cigarettes) go by many names, including but not limited to electronic nicotine delivery systems, vapes, vape pens, e-cigars, and hookah pens.

According to the American Academy of Pediatrics, as little as one teaspoon of liquid nicotine can be fatal to a 26-pound child. Even liquid nicotine spilled on the skin can be poisonous within minutes. Despite this trend all current evidence finds that e-cigarettes carry a fraction of the risk of smoking. By Robyn Correll, MPHCorrell holds a master of public health degree and has over a decade of experience working in the prevention of infectious diseases. Compared to the hot, harsh smoke of burning leaves, the aerosol made by vaporizers can feel much smoother on the lungs. While inhaling marijuana can harm your lungs, it’s used in other forms to help treat the symptoms of cancer and cancer treatments, such as chemotherapy.

Scientists are still learning more about how e-cigarettes affect health. However, there is already enough evidence to justify efforts to prevent e-cigarette use by young people. We know that the vapor from e-cigarettes is harmful because it contains harmful ingredients, including nicotine. Nicotine exposure during adolescence can cause addiction and can harm the developing brain. “When the risk of heart attack increases by as much as 55 percent among e-cigarettes users compared to nonsmokers, I wouldn’t want any of my patients nor my family members to vape,” Dr. Vindhyal said in the release. “When we dug deeper, we found that regardless of how frequently someone uses e-cigarettes, daily or just on some days, they are still more likely to have a heart attack or coronary artery disease.”

Upon entering the blood, nicotine stimulates the adrenal glands to release the hormone epinephrine (adrenaline). Epinephrine stimulates the central nervous system and increases blood pressure, breathing, and heart rate. As with most addictive substances, nicotine activates the brain’s reward circuits and also increases levels of a chemical messenger in the brain called dopamine, which reinforces rewarding behaviors. Pleasure caused by nicotine’s interaction with the reward circuit motivates some people to use nicotine again and again, despite risks to their health and well-being. Vapes oxva xlim pro pods, vaporizers, vape pens, hookah pens, electronic cigarettes (e-cigarettes or e-cigs), e-cigars, and e-pipes are some of the many tobacco product terms used to describe electronic nicotine delivery systems (ENDS).

Quick Facts on the Risks of E-cigarettes for Kids, Teens, and Young Adults. /tobacco/basic_information/e-cigarettes/Quick-Facts-on-the-Risks-of-E-cigarettes-for-Kids-Teens-and-Young-Adults.html. In 2023, 309.4 million units of e-cigarette products were sold in U.S. retail stores nationwide. E-cigarettes contain nicotine and lithium batteries, making them hazardous waste. Main Outcomes and Measures  The main outcome was age-adjusted prevalence of current and daily e-cigarette use overall and by participant characteristics, state, and territory.

We ask that you edit only for style or to shorten, provide proper attribution and link to our website. Please see our republishing guidelines for use of any other photos and graphics. Makers of alternatives to cigarettes are not clamoring to use this pathway. Increasing the appeal and streamlining the MRTP pathway will be necessary to ramp up applications from manufacturers.

Notably, the reverse was not true—students who said they smoked cigarettes were no more likely to report use of e-cigarettes when asked approximately 6 months later. Electronic cigarettes, or e-cigarettes, are tobacco products that have been sold in the U.S. for about a decade. They include e-pens, e-pipes, e-hookah, and e-cigars, known collectively as ENDS—electronic nicotine delivery systems. They’re also sometimes called JUULs, “vapes” and “vape pens.” E-cigarettes are the most commonly used tobacco products among kids—and it’s become an epidemic. While much remains to be determined about the lasting health consequences of e-cigarettes, there’s evolving evidence about the health risks of e-cigarettes on the lungs—including irreversible lung damage and lung disease.

They contain nicotine, propylene glycol, glycerin, flavorings, and potentially dangerous chemicals like formaldehyde and various metals. Products containing nicotine or tobacco can’t be legally sold to people under age 21, but the government has faced challenges in regulating sales of disposable, imported devices. Some 10% of high school students said last year they had used e-cigarettes in the previous month, down from 14% the previous year, according to a national survey. About 5% of middle school students said they recently used e-cigarettes. During the ban, the city will study stores that sell vaping products, seek public input veiik vape london, look at what other communities have done and consider zoning changes, said Doug Plowman, planning director.

In December 2019, the legislation was included in the federal year-end legislative package and passed by both houses of Congress. President Trump signed the bill into law on December 20, 2019 and it immediately took effect. This legislation, which applies to all states, raises the minimum age of sale for all tobacco products— including e-cigarette—to 21. On May 15, 2019 a federal judge sided with the American Lung Association and our partners in this lawsuit.

The FDA reports an alarming 900% rise in e-cigarette use among high school students from 2011 to 2015 and the number of high school students using them increased 78% in 2018 alone. Some individuals who smoke combustible tobacco products, such as cigarettes, cigars, and pipes, have been turning to electronic cigarettes (e-cigarettes) as an alternative to combustibles and as a smoking cessation tool. E-cigarettes are also commonly referred to as electronic nicotine devices, alternate nicotine devices, hookahs, vape pens, or e-cigs. Use of e-cigarettes and inhalation of their contents is known as vaping (American Cancer Society, 2022). Moreover, while the basic technology behind e-cigarettes is consistent, there is enormous variability within the product category and there is no typical e-cigarette. The products include different ingredients, different hardware and deliver highly variable amounts of nicotine and potentially toxic chemicals, including heavy metals such as cadmium, lead, nickel, tin and copper.

He feels the physical effects of his breathing every time he steps on the field. I could not believe my son had gotten caught up in this vaping epidemic. Jacob and I discussed it many times and he reassured me each time that he would never vape because he was an athlete and he didn’t want to mess up his lungs.

E-cigarettes are nicotine-based products, and no nicotine use is safe. Until we know more, it is probably best to avoid these products whenever possible, including secondhand smoke. However, vaping early on may increase the chances of smoking ordinary cigarettes later in life.

We calculated the optimal puff duration of 3 s every 30 s based on published data.16–21 This allows time for the vapour to condense between each puff and prevented overheating of the device; 1.4 mL of ECL/nicotine-free ECL (nfECL) was vaped from each device. On completion, suction traps were normalised to room temperature and spun at 1500g for 10 min to collect the condensate. The liquid and vapour contain some potentially harmful chemicals also found in cigarette smoke, but at a much lower level. Find out more about e-cigarettes, e-liquids and vaping to quit smoking on the Better Health website. FDA approved tobacco treatment medications can help people trying to quit smoking. These include over-the-counter and prescription options, which are known to be effective.

It may take some experimentation with different products and e-liquids to find the right one. With nicotine-containing products, vaping may be safer than smoking. It involves fewer hazardous chemicals and results in less lung damage.

The majority of respondents currently smoked cigarettes either daily (30.9%) or weekly (44.4%). Most respondents had been aware of the ban before the survey (67.7%), with a plurality feeling neutral about the ban (36.1%) but more supporting the ban than opposing it (35.9% vs. 28.1%). Among respondents who knew about the ban before the survey, the perceived compliance of local retailers with the ban as lower than 50% was quite high (66.2%), and relatively few perceived that more than 75% of retailers were complying (14.8%). On Dec. 21, 2022, California enacted Senate Bill 793, which prohibited the sale of most flavored tobacco products, including e-cigarettes, to people of all ages. Hookahs, premium cigars and loose-leaf tobacco were exempted from the legislation.

Almost half (49.1%) of young people don’t know what to do with used e-cigarette pods and disposable devices. Daily use of EVPs increased from 2% in 2015 to 7.2% in 2019, greater than three-and-one-half times increase. Although the percentage decreased to 5% in 2021, it was still more than a two-and-one-half increase since 2015. The researchers speculate that the effects of COVID-19, which included lockdowns and remote schooling, may have contributed to the decrease in 2021 but cautioned that further research is warranted.

They each have a mouthpiece, a battery, a heating element and a container for the vaping fluid, which is sometimes part of the mouthpiece. In the United States tpms motorcycle, marketing e-cigs to teens may have helped hook more young people on nicotine and tobacco. In August 2019, the FDA notified four companies to remove 44 flavored e-cigarette fluids and hookah tobaccos from sale in the United States. The agency crackdown underlined the FDA’s muscle-flexing on its authority to require FDA approval for new flavored products.

The Attorney General’s Office is committed to the enforcement of tobacco and nicotine control laws, including e-cigarette laws, and preventing youth access to these products. Secondhand smoke can cause heart disease, stroke, and lung cancer in people who don’t smoke. This toolkit is for Minnesota school staff, including administrators, educators, teachers, and health services staff, who are working to address the use of e-cigarettes in schools. It outlines opportunities for action, along with resources and tools to help youth quit. The U.S. Food and Drug Administration’s (FDA) “The Real Cost” campaign seeks to prevent susceptible youth from trying tobacco or becoming regular users. The campaign works to counteract the “cost-free” mentality held by many adolescents regarding e-cigarette use, showing them how e-cigarettes, just like cigarettes, puts them at risk for addiction and other health consequences.

Prior to the pandemic, the survey was conducted in person, inside the school classroom. Because of the changes in the way the survey was conducted this year, results of the 2021 NYTS cannot be compared to findings from previous surveys. A plain-language research summary that describes how e-cigarettes work, how safe they are compared to traditional… Table 3 demonstrates the prevalence of current and daily e-cigarette use across age groups and by combustible cigarette use. The prevalence of current e-cigarette use decreased with increasing age and was highest among young adults aged 18 to 20 years (18.1% [95% CI, 16.6%-19.6%]) and 21 to 24 years (18.6% [95% CI, 17.5%-19.7%]) (Figure and Table 3). Because most tobacco use starts during adolescence, actions to protect our nation’s young people from a lifetime of nicotine addiction are critical.

Linking to a non-federal website does not constitute an endorsement by ODPHP or any of its employees of the sponsors or the information and products presented on the website. Talk to your children’s pediatrician, who may be able to provide treatment or make a referral, if you are concerned that your child is vaping and/or addicted to vaping. As an example, NIDA point to the practice of “dripping.” This involves inhaling solutions dripped directly onto the heater coil “to produce a stronger throat hit.” The specific risks of these practices are still unclear. Experimenting with different ways of using vaping materials may be additionally risky. A website along with social media resources for teens to give them the facts about vaping and help them not become a tool. Primary spontaneous pneumothorax, or collapsed lung, occurs when there’s a hole in the lung through which oxygen escapes.

Find more information on Iowa’s e-cigarette-related laws and regulations from the Public Health Law Center at Mitchell Hamline School of Law. Besides nicotine, e-cigarette aerosol can contain harmful and cancer-causing chemicals. Defective batteries have caused fires and explosions resulting in serious injuries. More than 2.1 million students across the country reported using e-cigarettes in 2023, according to a survey study from the U.S. Common side effects of using Juul and other e-cigarettes include coughing, dizziness and dry mouth. Serious vaping side effects may include severe lung injuries, seizures, and nicotine addiction and poisoning.

Our range of starter kits, will include a personal vaporiser mod with an integrated battery, along with all the necessary components to get you started – one or two coils, a vape tank or pod, USB charging cable and spare parts. We stock vape kits from all the leading manufacturers each offering types of e-cigarettes to suit every vaper and types of vape juice, leading brands include SMOK vape kits, Aspire, Vaporesso, Elf Bar Vape and many more. The Electronic Cigarette Company reserves the right to cancel any sales transaction based on its sole discretion where it reasonably believes the purchaser is purchasing products on behalf of a minor. Great for new vapers, disposable vape kits are the simplest way to vape. Needing no extra coils or e-liquid to use they are an all-in-one package.

Nearly five times as many high school students use e-cigarettes than smoke cigarettes. Tetrahydrocannabinol (THC)-containing e-cigarette or vaping products was linked to most EVALI cases. Emergency department visits related to e-cigarette, or vaping, products have sharply declined in recent years, but the CDC continues to monitor reports.

If you have never smoked or used other tobacco products or e-cigarettes, do not start. Effective July 1, 2019, people must be at least 21 years old to buy tobacco products in Illinois, including e-cigarettes. While they may help some people stop smoking, vaping products do not have FDA approval as a tool for quitting. E-cigarettes may even keep people from trying proven methods of quitting smoking. People who switch from traditional cigarettes to e-products may put off getting medical help or trying proven tools that can help with quitting. A comparison of the serum levels of nicotine from e-cigarette or conventional cigarette consumption has been recently reported [39].

Law enforcement officers need to understand the value of collecting e-cigarette and vaping paraphernalia as evidence. Varenicline, perhaps better known by the brand name Chantix, is FDA-approved to help adults to stop smoking traditional cigarettes. But, despite the growing numbers of people who use e-cigarettes, there are no approved medication options to help them to stop using e-cigarettes. It made sense – Altria, the bad actor formerly known as Philip Morris, maker of Marlboro cigarettes, owned a 35% stake in JUUL. With so many adults kicking the cigarette smoking habit, Altria was looking for ways to sustain its financial stability. A French study from the same year found similar results, but also it found that e-cig use among smokers increased the risk of relapse into tobacco use.

Heating the liquid (e-juices) causes formation of an aerosol which users inhale into their lungs. These electronic smoking devices come in different shapes and sizes and can look like regular cigarettes, pens, and even flash drives (similar to the popular brand “JUUL”). E-cigarettes go by many names including vapes, e-cigs, e-pens, e-hookahs and mods.

At sub-cytotoxic levels both ECVC and nfECVC inhibited phagocytosis of E. Aureus, suggesting vaping might significantly impair bacterial clearance. Our data are supported by murine models in which mice exposed to e-cigarette vapour showed significantly impaired pulmonary bacterial clearance compared with air-exposed mice following an intranasal infection with Streptococcus pneumoniae. In vitro PAFR is significantly upregulated by inducers of oxidative stress such as traditional cigarette smoke. E-Cigarettes, also called personal vaporizers or “vapes”, present another way for smokers to ingest nicotine. E-Cigarettes have been marketed to young adults and adolescents through the use of candy and fruit flavors.

Researchers from Yale Cancer Center and MUSC Hollings Cancer Center published the results of their clinical trial of varenicline to help adults to stop using e-cigarettes in the American Journal of Preventive Medicine on May 16. The first U.S. trial of varenicline for e-cigarette cessation shows promising results and warrants larger-scale trials, the researchers say. Currently, over 80% of schools in Iowa have a comprehensive tobacco and nicotine-free policy. To view or search for local policies digiflavor danmark, search Tobacco Use Prevention and Control’s Policy Database. This video is about e-cigarettes and the emerging threat faced by rising youth use rates from Tobacco Control Network (TCN), Luci Longoria, and Dr. Brian King, FDA’s Center for Tobacco Products Director.

Although PG and glycerol are the major components of e-liquids other components have been detected. Of note купить смок норд 4, the analysis identified formaldehyde, acetaldehyde and acrolein [4], 3 carbonyl compounds with known high toxicity [63,64,65,66,67]. While no information was given regarding formaldehyde and acetaldehyde concentrations, the authors calculated that one puff could result in an acrolein exposure of 0.003–0.015 μg/mL [4].

Dr. Tan provides care to adults alongside an entire team of lung specialists at Loma Linda University Health. Our experts provide care to both kids and adults with complex lung issues from all over Southern California and beyond. Teens today have access to more potentially misleading information than at any other time in history. They’re also bombarded by more sources of advertising than ever before. Helping a teen understand what sources to trust can give them a powerful tool to educate themselves. Exposure to nicotine can also rewire a young brain to become more easily addicted to other substances, including cocaine and alcohol.

A survey by the WHO and the health ministry on students in 11 localities revealed that the rate of using e-cigarettes among students has been consistently rising among certain age groups. They are addictive as they contain nicotine, can cause diseases like cancer, and affect one’s mental health. With the menthol cigarette ban uncertain, the path for low-risk tobacco product authorization needs to be reimagined to nationally increase MRTP availability, access, and appeal among people who use menthol cigarettes. For example, one study among people who smoke showed that hypothetical general claims about completely switching to a heated tobacco MRTP outperformed specific claims—such as switching from cigarettes will reduce the risk of lung cancer and exposure to arsenic.

Strong decisive action is needed to prevent the uptake of e-cigarettes based on the growing body of evidence of its use by children and adolescents and health harms. Little research has been conducted into the safety of e-cigarettes and e-liquids in pregnancy. It is not known whether the vapour is harmful to a baby in pregnancy.

Most of the side effects were along the lines of nausea, insomnia or vivid dreams. A recent Italian study married pharmacotherapy with intense weekly behavioral counseling sessions, and the trial of cytisinicline also included weekly 10-minute sessions with trained counselors. E-cigarettes, however, can last for 5,000 or more puffs, making them harder to track intake but easier to use.

Nationally, e-cigarette use among high school students doubled from 11.7% in 2017 to 27.5% in 2019. Unlike cigarette butts, e-cigarette waste won’t biodegrade even under severe conditions. E-cigarettes left on the street eventually break down into microplastics and chemicals that flow into the storm drains to pollute our waterways and wildlife. In 2014, Hennekens received the prestigious Ochsner Award for Smoking and Health for reducing premature deaths from cigarettes, which was presented by the American College of Chest Physicians. Hennekens joined other luminaries who had previously received the award, including his mentors and colleagues, Professors Sir Richard Doll and Sir Richard Peto as well as Alton Ochsner, M.D. Study co-authors are Adedamola Adele, Department of Biomedical Science; Maria C. Mejia, M.D., professor of population health and social medicine; and Robert S. Levine, M.D., affiliate professor of family medicine, all within the Schmidt College of Medicine.

Disposable e-cigarettes, sometimes referred to as puff bars, have been designed as an affordable entry level device. Ready to use straight out of the box, disposables are the simplest type of device to use. We have lots of detailed vaping guides and blog posts to help new vapers make the transition to vaping. Find everything you need to know about e-liquids, starter kits, and what to expect when switching to vaping. Alternatively, why not speak to one of our customer service advisors?

The age restriction (21+) has only created an entrepreneurial opportunity. Kids are buying e-juice, filling cartridges and selling them to others not able to obtain product on their own. Indeed, the “vapor” may have a lot more than those five ingredients listed above. Some studies have found it to contain lead, nickel, tin, and silver from the machinery inside the devices along with formaldehyde, manganese, tolulene, and other ingredients linked to cancer, central nervous system problems, and other possible health issues. A 2018 study of e-cig smokers’ urine found at least five of the same carcinogens found in cigarettes. In addition, flavored tobacco products are known to make it difficult to quit nicotine.

No matter how it’s delivered, nicotine is harmful for youth and young adults. E-cigarettes typically contain nicotine as well as other chemicals that are known to damage health. For example, users risk exposing their respiratory systems to potentially harmful chemicals in e-cigarettes. Read about these and other risks young people face if they use e-cigarettes. Moreover, to the extent that those e-cigarette users who want to continue using banned flavors post-ban were able to do so, that would reduce the likelihood that they would quit e-cigarettes or turn to increased smoking, instead.

The nicotine content of the liquid can range from “very high” to zero. Refills come in flavors such as cool cucumber, mango, and mint, which may seem natural and harmless, but a single JUUL refill contains as much nicotine as a pack of 20 cigarettes. Some of the ingredients in e-cigarettes could also be harmful to the lungs in the long-term.

We show a significant increase in cytotoxicity caused by the vaping process itself. Importantly, exposure of macrophages to ECVC induced many of the same cellular and functional changes in AM function seen in cigarette smokers and patients with COPD. While further research is needed to fully understand the effects of e-cigarette exposure in humans in vivo, we suggest continued caution against the widely held opinion that e-cigarettes are safe. Third, our model represents an acute exposure, rather than a chronic exposure system which is better suited to in vivo animal experiments.

Well, if they have, it’s not public because that’s not a public process. But one can look around and see that no e-cigarettes have been approved for use as safe and effective cessation aids. Ultimately, the legal burden is on the companies to demonstrate that the benefit to adults is going to outweigh the harm to kids.

And more than a quarter (27.6%) of current youth e-cigarette users say they use an e-cigarette product every day. These electronic devices, also known as e-cigarettes, vapes, vape pens, personal vaporizers, e-cigars, pod systems, mods and e-hookah, are not a safe alternative to cigarette smoking. The report, published in the Morbidity and Mortality Weekly Report, was based on data from the 2021 National Youth Tobacco Survey (NYTS), a cross-sectional, self-administered survey of U.S. middle (grades 6–8) and high (grades 9–12) school students. The study assessed current (used on one or more of the past 30 days) e-cigarette use; frequency of use; and use by device type, flavors and usual brand. Centers for Disease Control and Prevention (CDC) estimated that more than 2 million U.S. middle and high school students reported currently using e-cigarettes in 2021, with more than 8 in 10 of those youth using flavored e-cigarettes. Research from The Johns Hopkins University on vape ingredients published in October 2021 reveals thousands of chemical ingredients in vape products oem tpms rims, most of which are not yet identified.

These devices are referred to by a variety of names, including “e-cigs,” “e-hookahs,” “mods,” “vape pens,” “vapes,” and “tank systems.” E-cigarettes can also be used to deliver other drugs besides nicotine, such as marijuana. E-cigarettes, also known as e-cigs, vapes, vape pens, and electronic nicotine delivery systems (ENDS), are experiencing rapid growth in popularity, especially among teens and young adults. They come in a variety of forms, sometimes looking like USB flash drives, pens, and other items that make them hard for parents and teachers to spot. Researchers said this could be due to decreased toxic effects of e-cigarette usage, early dissipation of the toxic effects, or the fact that it has not been studied long enough to show permanent damage to portray cardiovascular disease morbidity.

Yereth Rosen came to Alaska in 1987 to work for the Anchorage Times. She has reported for Reuters, for the Alaska Dispatch News, for Arctic Today and for other organizations. She covers environmental issues, energy, climate change, natural resources, economic and business news, health, science and Arctic concerns.

Vaporesso kits tend to downplay excessive features to provide straightforward function instead, with their LUXE Q range of MTL pod vapes being popular as starter kits. Their iTank range of MTL and DTL tanks also indicates a desire to keep more traditional forms of vape design alive. Elf Bar are undisputed kings of the disposable vape pens market, with simple to use and long-lasting disposable vape pens that do not require charging, refilling or even button-pressing. You simply remove the packaging and start to inhale to begin receiving Elf Bar’s notoriously flavoursome vape clouds.

This does not necessarily mean, however, that e-cigarettes are free from hazardous effects. Indeed, studies investigating their long-term effects on human health are urgently required. In this regard, the main additional studies needed in this field are summarized in Table 3. Other important components in the aerosols include silicate particles from the fiberglass wicks or silicone [89,90,91]. Many of these products are known to cause abnormalities in respiratory function and respiratory diseases [89,90,91], but more in-depth studies are required. Interestingly, the battery output voltage also seems to have an impact on the cytotoxicity of the aerosol vapours, with e-liquids from a higher battery output voltage showing more toxicity to A549 cells [30].

Research published in 2019 indicated many e-cigarette brands, including the popular JUUL brand, were specifically designed to be as addictive as Marlboro cigarettes, leading a new generation to nicotine addiction. Recent studies indicate disposable e-cigarettes are linked to higher vape rates among teens in the U.S. Teens and young adults who use them are more likely to keep vaping and vape more frequently. Even with these caveats, these findings warrant urgent attention from state agencies to enforce the ban on flavored e-cigarette products in California.

Many vapes don’t state they contain nicotine, even though they do, and often at high strengths. Some of the research for Tobacco Tactics was funded by Cancer Research UK Limited and Bloomberg Philanthropies. This work has previously received funding from The New Venture Fund, Smokefree South West, and the Economic and Social Research Council (ESRC) Knowledge Exchange Opportunities scheme. These funders have had no input into the research reported on this website or its conclusions. They are not responsible for its content or publication, nor do they necessarily endorse it. However, placement in an alternative school setting can lead to more severe outcomes, what many experts refer to as a school-to-prison pipeline.

It was not until months later that I understood, at which point my son had now been vaping every day for 3 months, 4 to 5 times a day. LEXINGTON, Ky. — Governor Andy Beshear, Ky-D, signed House Bill 11 into law in early April. It’s a bill that bans retailers from selling unauthorized vapor products. The wording of the bill has vape store owners concerned, and a lawsuit was filed shortly after it was passed to address this. But now that I’ve gotten rid of the endless, all-day vaping, and a nicotine hit makes me stink like a dive bar ashtray, makes my mouth taste like dirt, and makes my friends recoil from my presence, I’ve got reasons to cut back.

In addition, the research team delivered increasing concentrations of the nicotine over time, from 1% to 2.5%, to 5%. Another potential risk in studies of this type is the use of nonallocated products. As in previous studies, a much higher proportion of participants in the EC arm than in the other arms continued to use their product throughout the study period (63% vs 0%). The key question about long-term switching from smoking to EC use is whether this is a positive or a negative outcome.

While some young people may be able to quit e-cigarette use on their own, others, particularly daily users, are likely to find this to be very difficult. The ACS encourages adolescent users who find it difficult to quit to ask for help from health care professionals. Parents should learn all they can about e-cigarette use and be prepared to help their children get the assistance they need.

The FDA has not authorized any flavored e-cigarette products and reports that it has denied marketing applications for millions of flavored products. E-cigarette companies have filed over 60 lawsuits challenging the FDA’s marketing denial orders. In addition, while the FDA denied marketing applications for all Juul products in June 2022, it subsequently put that decision on hold in the face of a lawsuit by Juul.

The ACS does not recommend the use of e-cigarettes as a cessation method. No e-cigarette has been approved by the Food and Drug Administration (FDA) as a safe and effective cessation product. Even without regulatory changes, however, the research suggests that users may reduce potential harm by opting for e-cigarettes with freebase nicotine instead of nicotine salts or using e-cigarettes with a lower nicotine content. These examples are programmatically compiled from various online sources to illustrate current usage of the word ‘electronic cigarette.’ Any opinions expressed in the examples do not represent those of Merriam-Webster or its editors.

The chemical is not only highly addictive, but it can increase blood pressure and affect the flow of blood to the heart. It may also harden the arterial walls, which can lead to a heart attack. The FDA Commissioner released a statement regarding new enforcement actions and a plan to prevent youth e-cigarette use, specifically calling out JUUL, in August, 2018 and an additional statement in November 2018 with plans to limit access to flavored tobacco products.

Youth use of e-cigarettes continues to be an emerging public health challenge. Addressing this requires the collaboration of local, state and national partners along with those working directly with youth, such as school administrators, nurses, teachers and others to ensure all young people can learn in an environment free from e-cigarette use. However, e-cigarettes may help non-pregnant adult smokers if used as a complete substitute for all cigarettes and other smoked tobacco products.

In e-cigarettes, tobacco combustion is replaced by e-liquid heating, leading some manufacturers to propose that e-cigarettes have less harmful respiratory effects than tobacco consumption. Other innovative features such as the adjustment of nicotine content and the choice of pleasant flavours have won over many users. Nevertheless, the safety of e-cigarette consumption and its potential as a smoking cessation method remain controversial due to limited evidence. Moreover, it has been reported that the heating process itself can lead to the formation of new decomposition compounds of questionable toxicity.

Electronic cigarettes produce an aerosol by heating a liquid that usually contains nicotine, flavorings and other chemicals. Several states have imposed restrictions on the sale of e-cigarettes. There are also restrictions on liquids with flavors that may be more attractive to younger people. When the user sucks on the mouthpiece, the heating element vaporizes the solution, which the person then “vapes,” or inhales.

Their initial DRAG kits popularised the idea of pocket-friendly devices for sub-ohm pod vaping, making them one of the best vaping brands for innovation. If you were to return to 2010 in a time machine, you’d be stunned by how little there was on offer compared to today. And, these 10 best vape brands are behind some of the best vape kits, mods, and tanks, setting new standards in the vaping world.

If you need help choosing your first vape kit, or simply looking for an upgrade then get in touch or pop into one of our London based vaporizer stores. Depending on brand and device, some vape kits will have integrated batteries and others you’ll be required to purchase batteries separately. Consisting of an advanced box mod and suitably paired vape tank, Sub-Ohm kits are packed with plenty of features and offering variable voltage and wattage for a truly personalised vaping experience. The leading disposable vape kits are Elf Bars, Lost Mary and Crystal Bar. Both come in a wide range of tastes to suit anyone looking to switch from smoking but also work well as a cheap back up kit for existing vapers.

The longer ENDS and other e-cigarettes are on the market, the more information we know about their impacts on health. This includes data on youth use of these products, which has led to development of several educational programs designed to prevent adolescents and teens from using these products. Through tobacco product problem reports and tobacco product violation reports, the FDA also knows much more about many safety and health hazards they may pose. The American Lung Association will continue to urge FDA and Congress to remove all flavored tobacco products from the marketplace. Electronic cigarettes, or e-cigarettes, include e-pens, e-pipes, e-hookah, and e-cigars are known collectively as ENDS— electronic nicotine delivery systems. According to the FDA, e-cigarettes are devices that allow users to inhale an aerosol containing nicotine or other substances.

Respondents also reported keeping or selling the devices, or returning them to a vape shop. In addition, the percentage of EVP use in 2021 was higher in whites (6.5%) than Blacks (3.1%), Asians (1.2%), and Hispanic/Latinos (3.4%) compared to 2015. However, white and Black adolescents had the highest increases of about threefold between 2015 and 2021. In all four survey years, daily EVP use was highest in grade 12 where most students are ages 17 to 18.

Poison centers began receiving calls about e-cigarettes and liquid nicotine products in 2010, which overlaps with the initial period where these products reached the U.S. market. Detection and phagocytosis of pathogens is key to macrophage function and in many cases is the first step in orchestrating an immune response to infection in the airways. Any effect of e-cigarette vapour on the phagocytic ability of AMs is therefore of potential significance to the innate immune response in vivo.

Southern, western, and midwestern states generally had a higher prevalence of current e-cigarette use compared with other states, except for California (5.2% [95% CI, 4.5%-5.9%]) and Minnesota (5.7% [95% CI, 5.2%-6.2%]). Northeastern states generally had a lower prevalence of current e-cigarette use, except for Delaware (6.1% [95% CI, 5.1%-7.4%]), New Jersey (6.0% [95% CI, 5.2%-6.8%]), Pennsylvania (6.1% [95% CI, 5.3%-7.0%]), and Rhode Island (6.2% [95% CI, 5.1%-7.4%]). In the US territories, the prevalence varied widely from 2.0% (95% CI, 1.5%-2.7%) in Puerto Rico to 11.1% in Guam (95% CI, 8.8%-14.0%). Since e-cigarettes arrived on the market veiik 7000, there’s been a lot of buzz about them. In the past several years, many myths, safety concerns, and questions have come up. An electronic cigarette consists of an atomizer, a power source such as a battery,[26] and a container for e-liquid such as a cartridge or tank.

In this study, for example, many of those perceiving high levels of in-state retailer compliance still reported considerable use of e-cigarettes with banned flavors. As encouraging as the data was a few years ago, it’s starting to look like that’s not the case. The FDA is yet to approve them as a smoking cessation aid and a recent CDC study found that most adult e-cigarette users — 58.8 percent of them — don’t stop smoking cigarettes and instead wind up using both products. They seem like they have a lot of flavors that would make them appealing to [youth], but the harm with youth using nicotine products is there are unknowns with their long-term effects, and it also could lead to other product use. But on the other hand, they’re unquestionably safer than existing tobacco products. An expert independent evidence review published today by Public Health England (PHE) concludes that e-cigarettes are significantly less harmful to health than tobacco and have the potential to help smokers quit smoking.

Get the latest facts and analyses on the most important issues related to smoking, vaping, nicotine and substance use. If, at the time of application, the applicant holds a valid cigarette, cigar and/or tobacco retailer permit for the same business location, use Permit Fee Table Two below to calculate the permit fee due. If, at the time of application, the applicant does not hold a valid cigarette, cigar and /or tobacco retailer permit for the same business location, use Permit Fee Table One below to calculate the permit fee due. It’s easy to renew your retail tobacco and e-cigarette permits online. Prevention of diseases & conditions such as heart disease, cancer, diabetes and many others.

An e-cigarette is a battery-operated device that heats liquid into an aerosol that the user inhales. The devices come in various shapes and sizes and are known by different names including “e-cigs” and “vapes.”  Using an e-cigarette is sometimes called “vaping,” The e-cigarette is typically reusable with new cartridges or liquid refills depending on the brand and model. E-cigarettes typically operate on a rechargeable lithium-ion battery.

Dr. Charles H. Hennekens, the first author of the study, warned about the severe implications of vaping. Initially, in 2015, more boys (2.8%) were using EVPs compared to girls (1.1%). By 2021, this trend reversed with 5.6% of girls vaping compared to 4.5% of boys. The study highlighted not only the rise in general usage but also interesting shifts in demographic patterns. Meanwhile, a competitor has received federal approval for a stool-based colon cancer screening test to rival Exact Sciences’ similar Cologuard.

Finally, the report provides detailed information on advertising and promotional expenditures by domestic e-cigarettes manufacturers between 2015 and 2018. The Commission found that spending on advertising and promotion more than tripled in three years, from $197.8 million in 2015 to $643.6 million in 2018. Previous studies have shown that a majority of people using e-cigarettes want to quit. But it’s been unclear whether products used to stop smoking traditional combustible cigarettes would also work for e-cigarettes.

Even if you don’t think your kids vape, talk about it with them anyway so they know it’s unhealthy. Vaping is the inhaling of an aerosol (mist) created by an electronic cigarette (e-cigarette). To inform this work and evaluate the effectiveness of policy, the CDC Foundation is collecting and analyzing information about e-cigarette sales, teen e-cigarette use, and teens’ attitudes about the epidemic. Children are exposed to e-cigarette advertising online and on TV, in magazines and billboards. Although it is illegal for e-cigarettes to be sold to youth under age 21, they can be ordered online. Drop the Vape also directs users to the New York State Quitline for free and confidential quit-coaching via telephone, internet, and text, and free starter kits of nicotine replacement therapy (NRT) for eligible New Yorkers.

But levels are usually low and generally far lower than in tobacco cigarettes. Some of the harmful substances emitted in secondhand e-cigarette aerosols are similar to those in secondhand tobacco smoke. However, more research is needed to fully understand emissions from e-cigarettes and their impact on human health.

In addition to its toxicological effects on foetus development, nicotine can disrupt brain development in adolescents and young adults [44,45 voopoo argus pro 2,46]. Several studies have also suggested that nicotine is potentially carcinogenic (reviewed in [41]), but more work is needed to prove its carcinogenicity independently of the combustion products of tobacco [47]. In this latter regard, no differences were encountered in the frequency of tumour appearance in rats subjected to long-term (2 years) inhalation of nicotine when compared with control rats [48]. Despite the lack of carcinogenicity evidence, it has been reported that nicotine promotes tumour cell survival by decreasing apoptosis and increasing proliferation [49], indicating that it may work as a “tumour enhancer”. In a very recent study, chronic administration of nicotine to mice (1 mg/kg every 3 days for a 60-day period) enhanced brain metastasis by skewing the polarity of M2 microglia, which increases metastatic tumour growth [50].

Among adolescents, marijuana vaping was significantly more likely to cause symptoms of lung injury. Even where cannabis is legal for medical use, you should still make sure the products you choose are legal and fully tested. Dispensaries should be able to provide a full report of the product’s lab results. Beware of those that don’t charge a sales tax or evade other regulations, which may increase your risk of illness or injury. E-cigarette flavorings damage human blood vessel cells grown in the lab even in the absence of nicotine, Stanford researchers and their colleagues found.

Electronic smoking devices (ESDs) do not just emit “harmless water vapor.” Secondhand aerosol (incorrectly called vapor by the industry) from ESDs contains nicotine, ultrafine particles and low levels of toxins that are known to cause cancer. In May 2015, Oregon expanded the Oregon Indoor Clean Air Act (ICAA) to include the use of “inhalant delivery systems,” which include e-cigarettes, vape pens, e-hookah and other devices. Under the law, Oregonians may not use e-cigarettes and other inhalant delivery systems in workplaces, restaurants, bars and other indoor public places in Oregon. Instead of smoke from burning tobacco, e-cigarette users inhale aerosol, or vapor, consisting of nicotine, flavor additives and other chemicals. We have validated a simple, cheap and effective system for condensing vaped ECL vapour to enable in vitro work.

As of April 30, 2024, Poison Centers have managed 2,816 e-cigarette and liquid nicotine related exposure cases. When users inhale from the end of an e-cigarette, a battery-operated device heats a liquid solution (e-liquid or e-juice) into an aerosol. Use of e-cigarettes mimics conventional cigarette smoking, and e-cigarettes also contain the same addictive ingredient, nicotine. Results Macrophage culture with ECL or ECVC resulted in a dose-dependent reduction in cell viability. ECVC was cytotoxic at lower concentrations than ECL and resulted in increased apoptosis and necrosis. Exposure of AMs to a sub-lethal 0.5% ECVC/nfECVC increased ROS production approximately 50-fold and significantly inhibited phagocytosis.

But is smoking e-cigarettes (also called vaping) better for you than using tobacco products? Michael Blaha, M.D., M.P.H., director of clinical research at the Johns Hopkins Ciccarone Center for the Prevention of Heart Disease, shares health information about vaping. The large increase in the percent of respondents using non-flavored instead of flavored e-cigarettes after the bans could produce public health gains, as added flavors can increase the toxicity of inhaled e-cigarette aerosols (24, 25). In addition, further research is needed to explore whether allowing only non-flavored e-cigarettes might be more beneficial for public health than also allowing tobacco-flavored versions. This is especially important if other measures are implemented to push smokers away from smoked tobacco products or to attract smokers to e-cigarettes, making using flavors to attract smokers less necessary or unnecessary at all.

Users have reported a growing list of potential e-cigarette side effects such as seizures, strokes, respiratory failure and bronchiolitis obliterans organizing pneumonia, or BOOP. The AMA promotes the art and science of medicine and the betterment of public health. The AMA has been a leading force to eliminate public smoking and warn people about the dangers of smoking, including secondhand smoke, since the 1960s.

2 Average reductions in levels of a range of harmful chemicals (excluding nicotine) compared to the smoke of a reference cigarette (3R4F). 1 Average reductions in levels of a range of harmful chemicals (excluding nicotine) compared to the smoke of a reference cigarette (3R4F). These smoke-free products are not risk-free, as they provide nicotine, which is addictive.

The study, one of the largest to date looking at the relationship between e-cigarette use and cardiovascular and other health outcomes and among the first to establish an association. The findings were spotlighted in a Popular Science article, which referenced another study led by Paul Ndunda, M.D., also an assistant professor in Internal Medicine at KU School of Medicine-Wichita. “Until now, little has been known about cardiovascular events relative to e-cigarette use,” Dr. Vindhyal, assistant professor in Internal Medicine at KU School of Medicine-Wichita, stated in the ACC release. “These data are a real wake-up call and should prompt more action and awareness about the dangers of e-cigarettes.”